Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
USERS' SCORE
Good
Based on 7 Reviews
8.4
Supplement Facts
Serving Size: 1 Vegetarian Tablet
Amount Per Serving
%DV
Folate [as (6S)-5-Methyltetrahydrofolate, Calcium salt]
1,700 mcg○
425%
Top Medical Research Studies
8
Folic acid treatment shows promise
We explored the effects of folic acid on hair loss in a three-week-old Charolais calf showing signs typical of folic acid deficiency. After starting daily folic acid therapy at a dose of 1 mg/kg, we observed that the crusts and patches diminished within two weeks. Remarkably, hair growth resumed, and within two months, the calf returned to a normal state. This indicates that folic acid could be an effective treatment for certain types of alopecia related to deficiencies in this essential nutrient.
Read More
8
We explored the effectiveness of two nutritional supplements for treating telogen effluvium (TE), a common form of hair loss. Over 180 days, female participants received either a nutrient-rich supplement containing folic acid or an alternative formulation.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Read More
7
We explored the effects of folic acid on hair loss in zebrafish larvae after exposure to different concentrations of ethanol. This study revealed how gestational ethanol exposure can harm the development of sensory hair cells. We found that even small amounts of ethanol lead to a significant decrease in hair cell count.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
Read More
Most Useful Reviews
9
Eliminated hair loss
1 people found this helpful
Very effective. A daily intake of 1000 mcg raises Ferritin levels, effectively eliminating fatigue and hair loss.
Read More
9
Fundamental supplement
1 people found this helpful
Excellent for anyone needing to take folate! I experience significant hair loss as well as greys, and this supplement has been fundamental! I recommend it!
Read More
7.5
Restored hair growth
1 people found this helpful
An effective supplement for hair loss. After just one week, I noticed improvements, along with restoration of my menstrual cycle. Just one small pill does the trick.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
- All Researches
8
We explored the effectiveness of two nutritional supplements for treating telogen effluvium (TE), a common form of hair loss. Over 180 days, female participants received either a nutrient-rich supplement containing folic acid or an alternative formulation.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Read More
8
Folic acid treatment shows promise
We explored the effects of folic acid on hair loss in a three-week-old Charolais calf showing signs typical of folic acid deficiency. After starting daily folic acid therapy at a dose of 1 mg/kg, we observed that the crusts and patches diminished within two weeks. Remarkably, hair growth resumed, and within two months, the calf returned to a normal state. This indicates that folic acid could be an effective treatment for certain types of alopecia related to deficiencies in this essential nutrient.
Read More
7
We investigated the effects of folate within a well-structured study that examined its role in hair loss treatments. Although part of a marketed oral combination for diffuse hair loss, folate's specific impact was challenging to isolate because it was evaluated alongside other compounds.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
Read More
7
We explored the effects of folic acid on hair loss in zebrafish larvae after exposure to different concentrations of ethanol. This study revealed how gestational ethanol exposure can harm the development of sensory hair cells. We found that even small amounts of ethanol lead to a significant decrease in hair cell count.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Eliminated hair loss
1 people found this helpful
Very effective. A daily intake of 1000 mcg raises Ferritin levels, effectively eliminating fatigue and hair loss.
Read More
9
Fundamental supplement
1 people found this helpful
Excellent for anyone needing to take folate! I experience significant hair loss as well as greys, and this supplement has been fundamental! I recommend it!
Read More
7.5
Restored hair growth
1 people found this helpful
An effective supplement for hair loss. After just one week, I noticed improvements, along with restoration of my menstrual cycle. Just one small pill does the trick.
Read More
10
Prevented folate depletion
Saved me from Methotrexate folate depletion! Currently on Methotrexate for RA, I was prescribed Folic Acid to counteract depletion. Despite my effort, I experienced severe symptoms—painful mouth sores and hair loss. After research, I learnt that some cannot absorb folic acid well. L-Methylfolate is easier to absorb, so I tried this brand. My symptoms slowly disappeared, and I felt improvements within weeks. These supplements saved me from the awful side effects associated with folate loss and Methotrexate.
Read More
8
Quality effects noted
It is of good quality and has worked excellently for me. Alongside CoQ10, it is well-priced, and the ingredient is highly beneficial for hair loss.
Read More
Frequently Asked Questions
7.5
Restored hair growth
1 people found this helpful
An effective supplement for hair loss. After just one week, I noticed improvements, along with restoration of my menstrual cycle. Just one small pill does the trick.
10
Prevented folate depletion
Saved me from Methotrexate folate depletion! Currently on Methotrexate for RA, I was prescribed Folic Acid to counteract depletion. Despite my effort, I experienced severe symptoms—painful mouth sores and hair loss. After research, I learnt that some cannot absorb folic acid well. L-Methylfolate is easier to absorb, so I tried this brand. My symptoms slowly disappeared, and I felt improvements within weeks. These supplements saved me from the awful side effects associated with folate loss and Methotrexate.
9
Eliminated hair loss
1 people found this helpful
Very effective. A daily intake of 1000 mcg raises Ferritin levels, effectively eliminating fatigue and hair loss.
9
Fundamental supplement
1 people found this helpful
Excellent for anyone needing to take folate! I experience significant hair loss as well as greys, and this supplement has been fundamental! I recommend it!
8
Quality effects noted
It is of good quality and has worked excellently for me. Alongside CoQ10, it is well-priced, and the ingredient is highly beneficial for hair loss.
7.5
Stopped hair fall
Verified manufacturer; I took this on my doctor's recommendation. In complex therapy, it helped to stop hair loss. The pills are not large and are easy to swallow. This is not the first time I have bought from this brand, and I am satisfied.
8
We explored the effectiveness of two nutritional supplements for treating telogen effluvium (TE), a common form of hair loss. Over 180 days, female participants received either a nutrient-rich supplement containing folic acid or an alternative formulation.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
8
Folic acid treatment shows promise
We explored the effects of folic acid on hair loss in a three-week-old Charolais calf showing signs typical of folic acid deficiency. After starting daily folic acid therapy at a dose of 1 mg/kg, we observed that the crusts and patches diminished within two weeks. Remarkably, hair growth resumed, and within two months, the calf returned to a normal state. This indicates that folic acid could be an effective treatment for certain types of alopecia related to deficiencies in this essential nutrient.
7
We investigated the effects of folate within a well-structured study that examined its role in hair loss treatments. Although part of a marketed oral combination for diffuse hair loss, folate's specific impact was challenging to isolate because it was evaluated alongside other compounds.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
References
- Sant'Anna Addor FA, Donato LC, Melo CSA. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Clin Cosmet Investig Dermatol. 2018;11:431. doi:10.2147/CCID.S173082
- Bouvet A, Baird JD, Basrur PK. Folic acid therapy for alopecia in a Charolais calf. Vet Rec. 1988;123:533.
- Riegel K, Hengl T, Krischok S, Schlinzig K, Abts HF. L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes. Clin Cosmet Investig Dermatol. 2020;13:499. doi:10.2147/CCID.S254720
- Rah YC, Park S, Koun S, Park HC, Choi J. In vivo assay of the ethanol-induced embryonic hair cell loss and the protective role of the retinoic and folic acid in zebrafish larvae (Danio rerio). Alcohol. 2019;75:113. doi:10.1016/j.alcohol.2018.07.008
